midlife metabolic switch
3 Longevity Science Dropoffs vs Midlife Smooth Aging?
Biological age tends to jump at roughly 40, 60 and 80 rather than rise in a straight line, and targeting those spikes can flatten the curve. By timing interventions around each drop-off, we can preserve function and stretch healthspan. 2025 saw a randomized trial of 1,200 participants where time-restricted